M.A. McDonough

The Obesity-Associated <i>FTO</i> Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Thomas Gerken, Christophe A. Girard, Yi‐Chun Loraine Tung et al. · Science · 2007 · 1.5K citations · Full text

The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases

Rasheduzzaman Chowdhury, Kar Kheng Yeoh, Ya‐Min Tian et al. · EMBO Reports · 2011 · 1K citations · Full text

Histone Modifications, Chromatin, Biochemistry +6

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)

M.A. McDonough, Vivian Li, Emily Flashman et al. · Proceedings of the National Academy of Sciences · 2006 · 365 citations · Full text

Redox Signaling, Crystal Structure, Transcriptional Regulation +14

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

Stanley S. Ng, K.L. Kavanagh, M.A. McDonough et al. · Nature · 2007 · 320 citations

Chromatin, Chromatin Structure, Biochemistry +12

Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α

Patrick J. Pollard, Christoph Loenarz, David R. Mole et al. · Biochemical Journal · 2008 · 290 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +19