Kirsty S. Hewitson

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

Andrew Epstein, Jonathan Gleadle, Luke A. McNeill et al. · Cell · 2001 · 3.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +9

The Obesity-Associated <i>FTO</i> Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Thomas Gerken, Christophe A. Girard, Yi‐Chun Loraine Tung et al. · Science · 2007 · 1.5K citations · Full text

Life Sciences, Genetics, Molecular Biology +9

Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family

Kirsty S. Hewitson, Luke A. McNeill, Madeline V. Riordan et al. · Journal of Biological Chemistry · 2002 · 716 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Structure of Factor-inhibiting Hypoxia-inducible Factor (HIF) Reveals Mechanism of Oxidative Modification of HIF-1α

Jonathan M. Elkins, Kirsty S. Hewitson, Christopher J. Schofield · Journal of Biological Chemistry · 2003 · 390 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)

M.A. McDonough, Vivian Li, Emily Flashman et al. · Proceedings of the National Academy of Sciences · 2006 · 368 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16