Jonathan Gleadle

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

Andrew Epstein, Jonathan Gleadle, Luke A. McNeill et al. · Cell · 2001 · 3.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +9

Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor

Rebecca J. Appelhoff, Ya‐Min Tian, Raju R. Raval et al. · Journal of Biological Chemistry · 2004 · 1.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth

Patrick H. Maxwell, Gabi U. Dachs, Jonathan Gleadle et al. · Proceedings of the National Academy of Sciences · 1997 · 1.1K citations · Full text

Medicine, Molecular Biology, Oncology +17

Hypoxic enhancement of exosome release by breast cancer cells

Hamish W. King, Michael Michael, Jonathan Gleadle · BMC Cancer · 2012 · 1.1K citations · Full text

Medicine, Cell Biology, Oncology +16

Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family

Kirsty S. Hewitson, Luke A. McNeill, Madeline V. Riordan et al. · Journal of Biological Chemistry · 2002 · 716 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13