Raphaël Frédérick

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

Luc Pilotte, Pierre Larrieu, Vincent Stroobant et al. · Proceedings of the National Academy of Sciences · 2012 · 564 citations · Full text

Immunotoxicology, Immunology, Immunoediting +18

Lactate Dehydrogenase B Controls Lysosome Activity and Autophagy in Cancer

Lucie Brisson, Piotr Bański, Martina Sboarina et al. · Cancer Cell · 2016 · 223 citations · Full text

Tumor Biology, Mitophagy, Cell Autophagy +9

Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators

Eduard Dolušić, Pierre Larrieu, Laurence Moineaux et al. · Journal of Medicinal Chemistry · 2011 · 180 citations · Full text

Immunology, Tryptophan Degradation, Cell Death +19

Synthesis and Biological Evaluation of Novel Analogues of the Pan Class I Phosphatidylinositol 3-Kinase (PI3K) Inhibitor 2-(Difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1<i>H</i>-benzimidazole (ZSTK474)

Gordon W. Rewcastle, Swarna A. Gamage, Jack U. Flanagan et al. · Journal of Medicinal Chemistry · 2011 · 103 citations · Full text

Novel Trisubstituted Harmine Derivatives with Original in Vitro Anticancer Activity

Raphaël Frédérick, Céline Bruyère, Christelle Vancraeynest et al. · Journal of Medicinal Chemistry · 2012 · 82 citations · Full text

Pharmacotherapy, Pharmaceutical Chemistry, Tumor Biology +20