Concepedia

Simon Klaessens

SK

Statistics

Publications

5

Citations

274

H-Index

5

Active since

2014

Affiliations

Ludwig Cancer Research(Current)

de Duve Institute

Walloon Excellence in Lifesciences and Biotechnology

Directorate-General Joint Research Centre

Cliniques Universitaires Saint-Luc

Simon Klaessens is an author at Ludwig Cancer Research specializing in indoleamine 2, 3-dioxygenase pathway, essential amino acid metabolism, and pharmacology.

ORCID

Publications per year

2014–2023

5

Publications

5

Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes

Marie Solvay, Simon Klaessens, Luc Pilotte et al. · Journal for ImmunoTherapy of Cancer · 2023 · 112 citations · Full text

, , +8

A novel cancer-germline transcript carrying pro-metastatic miR-105 and<i>TET</i>-targeting miR-767 induced by DNA hypomethylation in tumors

Axelle Loriot, Aurélie Van Tongelen, Jordi Blanco et al. · Epigenetics · 2014 · 68 citations · Full text

, , +17

Tryptophan 2,3-Dioxygenase Expression Identified in Human Hepatocellular Carcinoma Cells and in Intratumoral Pericytes of Most Cancers

Delia Hoffmann, Tereza Dvořáková, Vincent Stroobant et al. · Cancer Immunology Research · 2019 · 57 citations · Full text

, , +13

Tryptophanemia is controlled by a tryptophan-sensing mechanism ubiquitinating tryptophan 2,3-dioxygenase

Simon Klaessens, Vincent Stroobant, Delia Hoffmann et al. · Proceedings of the National Academy of Sciences · 2021 · 19 citations · Full text

, , +15

Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase

Arina Kozlova, Léopold Thabault, Maxime Liberelle et al. · Journal of Medicinal Chemistry · 2021 · 18 citations · Full text

, , +16

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