Narendran G-Dayanandan

Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents

Behnoush Hajian, Eric W. Scocchera, Carolyn Shoen et al. · Cell chemical biology · 2019 · 66 citations · Full text

Pulmonary Tuberculosis, Drug Target, Biochemistry +11

Propargyl-Linked Antifolates are Dual Inhibitors of <i>Candida albicans</i> and <i>Candida glabrata</i>

Narendran G-Dayanandan, Janet L. Paulsen, Kishore Viswanathan et al. · Journal of Medicinal Chemistry · 2014 · 50 citations · Full text

Fungal Cell Biology, Clinical Mycology, Pharmacotherapy +22

Crystal Structures of Trimethoprim-Resistant DfrA1 Rationalize Potent Inhibition by Propargyl-Linked Antifolates

Michael N. Lombardo, Narendran G-Dayanandan, Dennis L. Wright et al. · ACS Infectious Diseases · 2015 · 42 citations · Full text

Elucidating Features That Drive the Design of Selective Antifolates Using Crystal Structures of Human Dihydrofolate Reductase

K.M. Lamb, Narendran G-Dayanandan, Dennis L. Wright et al. · Biochemistry · 2013 · 40 citations · Full text

Aldo-keto Reductase, Molecular Biology, Analytical Ultracentrifugation +17

Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations

Stephanie M. Reeve, Eric W. Scocchera, Jacob Ferreira et al. · Journal of Medicinal Chemistry · 2016 · 31 citations · Full text

Promising Lead Series, Molecular Biology, Antimicrobial Chemotherapy +17