Carolyn McHale

Statistics

Publications

Citations

580

H-Index

Active since

2007

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

United States Military Academy

IRBM Science Park

Carolyn McHale is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in viral hepatitis, medicinal chemistry, and antiviral pharmacology.

Publications per year

2007–2022

Publications

MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants

Vincenzo Summa, Steven W. Ludmerer, John A. McCauley et al. · Antimicrobial Agents and Chemotherapy · 2012 · 255 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +16

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor

Steven J. Harper, John A. McCauley, Michael T. Rudd et al. · ACS Medicinal Chemistry Letters · 2012 · 201 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A time-resolved, internally quenched fluorescence assay to characterize inhibition of hepatitis C virus nonstructural protein 3–4A protease at low enzyme concentrations

Shi‐Shan Mao, Jillian DiMuzio, Carolyn McHale et al. · Analytical Biochemistry · 2007 · 30 citations

Life Sciences, Biochemistry, Molecular Biology +14

A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells

Keith P. Moore, Adam G. Schwaid, Matthew Tudor et al. · ACS Chemical Biology · 2022 · 27 citations

Medicine, Medicinal Chemistry, Pharmacology +16

P2‐Quinazolinones and Bis‐Macrocycles as New Templates for Next‐Generation Hepatitis C Virus NS3/4a Protease Inhibitors: Discovery of MK‐2748 and MK‐6325

Michael T. Rudd, John W. Butcher, Kevin T. Nguyen et al. · ChemMedChem · 2015 · 23 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

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