Keith P. Moore

First Demonstration of Cerebrospinal Fluid and Plasma Aβ Lowering with Oral Administration of a β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor in Nonhuman Primates

Sethu Sankaranarayanan, Marie A. Holahan, Dennis Colussi et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 105 citations

Synthesis of Complex Druglike Molecules by the Use of Highly Functionalized Bench‐Stable Organozinc Reagents

Thomas J. Greshock, Keith P. Moore, Ray T. McClain et al. · Angewandte Chemie International Edition · 2016 · 61 citations

Combinatorial Chemistry, Bioorganic Chemistry, Chemical Analysis +21

Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors

Stacey R. Lindsley, Keith P. Moore, Hemaka A. Rajapakse et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 47 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Medicine +6

Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors

Keith P. Moore, Hong Zhu, Hemaka A. Rajapakse et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 43 citations · Full text

Medicine, Brain Penetration, Neuropharmacology +9

Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors

Izzat T. Raheem, Abbas M. Walji, Daniel J. Klein et al. · Journal of Medicinal Chemistry · 2015 · 36 citations

Lead Compounds, Pharmacotherapy, Antiviral Drug +19