Yoshiharu Tsubamoto

PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance

Naoto Kubota, Yasuo Terauchi, Hiroshi Miki et al. · Molecular Cell · 1999 · 1.4K citations · Full text

Insulin Resistance, Obesity, Metabolic Syndrome +10

Inhibition of gastric inhibitory polypeptide signaling prevents obesity

Kazumasa Miyawaki, Yuichiro Yamada, Nobuhiro Ban et al. · Nature Medicine · 2002 · 941 citations

Obesity, Metabolic Syndrome, Gastric Inhibitory +9

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

Naoto Kubota, Kazuyuki Tobe, Yasuo Terauchi et al. · Diabetes · 2000 · 524 citations · Full text

Insulin Receptor, Insulin Signaling, Causes Type 2 +20

Role of NADH Shuttle System in Glucose-Induced Activation of Mitochondrial Metabolism and Insulin Secretion

Kazuhiro Eto, Yoshiharu Tsubamoto, Yasuo Terauchi et al. · Science · 1999 · 488 citations

Glucokinase and IRS-2 are required for compensatory   cell hyperplasia in response to high-fat diet-induced insulin resistance

Yasuo Terauchi, I. Takamoto, Naoto Kubota et al. · Journal of Clinical Investigation · 2007 · 327 citations · Full text