Inhibition of gastric inhibitory polypeptide signaling prevents obesity

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans

Robert V. Considine, Madhur K. Sinha, Mark L. Heiman et al. · New England Journal of Medicine · 1996 · 6.3K citations

Medicine, Endocrinology, Nutritional Sciences +7

The hormone resistin links obesity to diabetes

Claire M. Steppan, Shannon T. Bailey, Savitha Bhat et al. · Nature · 2001 · 4.8K citations

Life Sciences, Biochemistry, Endocrinology +12

Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> Gene

Jeffrey L. Halaas, K.S. Gajiwala, Margherita Maffei et al. · Science · 1995 · 4.5K citations

Medicine, Endocrinology, Nutritional Sciences +17

Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? 1962.

James V. Neel · PubMed · 1999 · 2.5K citations

Life Sciences, Biology, Genetics +13