Lisette G. G. C. Verhoef

Small molecule RITA binds to p53, blocks p53–HDM-2 interaction and activates p53 function in tumors

Natalia Issaeva, Przemyslaw Bozko, Martin Enge et al. · Nature Medicine · 2004 · 740 citations

P53 Function, Small Molecule Rita, Medicine +9

Aggregate formation inhibits proteasomal degradation of polyglutamine proteins

Lisette G. G. C. Verhoef · Human Molecular Genetics · 2002 · 294 citations

Protein Chemistry, Neurodegenerative Diseases, Protein Function +15

Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation

Kristina Lindsten, Femke M.S. de Vrij, Lisette G. G. C. Verhoef et al. · The Journal of Cell Biology · 2002 · 224 citations · Full text

Endoplasmic reticulum stress compromises the ubiquitin–proteasome system

Victoria Menéndez-Benito, Lisette G. G. C. Verhoef, Maria G. Masucci et al. · Human Molecular Genetics · 2005 · 220 citations · Full text

Threshold-controlled ubiquitination of the EGFR directs receptor fate

Sara Sigismund, Veronica Algisi, Gilda Nappo et al. · The EMBO Journal · 2013 · 174 citations · Full text

Threshold-controlled Ubiquitination, Signal Transduction, G Protein-coupled Receptor +5