Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells

Nico P. Dantuma, Kristina Lindsten, Rickard Glas, +2

Nature Biotechnology

Living CellsProtein FunctionBiochemistryProtein FoldingMedicine +10

Inhibition of proteasome deubiquitinating activity as a new cancer therapy

Pádraig D’Arcy, Slavica Brnjic, Maria Hägg Olofsson, +8

Nature Medicine

Proteasome Deubiquitinating ActivityOncologyMedicinePharmacologyProteasome +8

Viral immune modulators perturb the human molecular network by common and unique strategies

Andreas Pichlmair, Kumaran Kandasamy, Gualtiero Alvisi, +20

Nature

Viral ReplicationSystems BiologyViral Immune ModulatorsHuman Molecular NetworkViral Persistence +9

A transgenic mouse model of the ubiquitin/proteasome system

Kristina Lindsten, Victoria Menéndez-Benito, Maria G. Masucci, +1

Nature Biotechnology

Knockout MouseProtein FunctionMedicineProteasomeTransgenic Mouse Model +2

Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation

Kristina Lindsten, Femke M.S. de Vrij, Lisette G. G. C. Verhoef, +5

The Journal of Cell Biology

The ER‐resident ubiquitin‐specific protease 19 participates in the UPR and rescues ERAD substrates

Gerco Hassink, Bin Zhao, Ramakrishna Sompallae, +5

EMBO Reports

Protein FunctionMedicineNatural SciencesProteasomeMolecular Biology +5

Lack of Proteasome Active Site Allostery as Revealed by Subunit-Specific Inhibitors

Jayhyuk Myung, Kyung Bo Kim, Kristina Lindsten, +2

Molecular Cell

Subunit-specific InhibitorsProtein FunctionProtein AssemblyBiochemistryProtein Folding +6

Inhibition of proteasomal degradation by the Gly-Ala repeat of Epstein–Barr virus is influenced by the length of the repeat and the strength of the degradation signal

Nico P. Dantuma, Stijn Heessen, Kristina Lindsten, +2

Proceedings of the National Academy of Sciences

Ubiquitin-specific Protease 19 (USP19) Regulates Hypoxia-inducible Factor 1α (HIF-1α) during Hypoxia

Mikael Altun, Bin Zhao, Kelly Velasco, +5

Journal of Biological Chemistry

Ubiquitin-specific Protease 19Hypoxia-inducible Factor 1αCell DeathUbiquitin-proteasome SystemRedox Biology +18

The ubiquitin specific protease 4 (USP4) is a new player in the Wnt signalling pathway

Bin Zhao, Claudia Schlesiger, Maria G. Masucci, +1

Journal of Cellular and Molecular Medicine

ProteasomeMolecular BiologySignaling PathwayCell RegulationCanonical Wnt Signalling +15