J. Lépagnol

New Prolyl Endopeptidase Inhibitors:  <i>In Vitro</i> and <i>in Vivo</i> Activities of Azabicyclo[2.2.2]octane, Azabicyclo[2.2.1]heptane, and Perhydroindole Derivatives

Bernard Portevin, Alain Benoist, G. REMOND et al. · Journal of Medicinal Chemistry · 1996 · 90 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Pharmaceutical Science +14

Structure−Activity Relationships in a Series of 2(1<i>H</i>)-Quinolones Bearing Different Acidic Function in the 3-Position:  6,7-Dichloro-2(1<i>H</i>)-oxoquinoline-3-phosphonic Acid, a New Potent and Selective AMPA/Kainate Antagonist with Neuroprotective Properties

Patrice Désos, J. Lépagnol, Philippe Morain et al. · Journal of Medicinal Chemistry · 1996 · 77 citations

4<i>H</i>-1,2,4-Pyridothiadiazine 1,1-Dioxides and 2,3-Dihydro-4<i>H</i>-1,2,4-pyridothiadiazine 1,1-Dioxides Chemically Related to Diazoxide and Cyclothiazide as Powerful Positive Allosteric Modulators of (<i>R</i>/<i>S</i>)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors:  Design, Synthesis, Pharmacology, and Structure−Activity Relationships

Bernard Pirotte, Tchao Podona, Ousmane Diouf et al. · Journal of Medicinal Chemistry · 1998 · 60 citations

Ampa Receptor Modulator, Pharmacotherapy, Chemistry +19

A new rapid method for phospholipid separation by high-performance liquid chromatography with light-scattering detection

Lionel Breton, Bernard Serkiz, Jean‐Paul Volland et al. · Journal of Chromatography B Biomedical Sciences and Applications · 1989 · 53 citations

Lipid Analysis, Biochemistry, Separation Science +13

Competitive inhibition by NBQX of kainate/AMPA receptor currents and excitatory synaptic potentials: importance of 6-nitro substitution

John C.R. Randle, Thierry Guet, Alexis A. Cordi et al. · European Journal of Pharmacology · 1992 · 51 citations

Neurophysiology, Medicine, Synaptic Transmission +13