Philippe Morain

Dissociating β-Amyloid from α7 Nicotinic Acetylcholine Receptor by a Novel Therapeutic Agent, S 24795, Normalizes α7 Nicotinic Acetylcholine and NMDA Receptor Function in Alzheimer's Disease Brain

Hoau-Yan Wang, Andres Stucky, Jingjing Liu et al. · Journal of Neuroscience · 2009 · 100 citations · Full text

Structure−Activity Relationships in a Series of 2(1<i>H</i>)-Quinolones Bearing Different Acidic Function in the 3-Position:  6,7-Dichloro-2(1<i>H</i>)-oxoquinoline-3-phosphonic Acid, a New Potent and Selective AMPA/Kainate Antagonist with Neuroprotective Properties

Patrice Désos, J. Lépagnol, Philippe Morain et al. · Journal of Medicinal Chemistry · 1996 · 77 citations

S 17092-1, a Highly Potent, Specific and Cell Permeant Inhibitor of Human Proline Endopeptidase

Hélène Barelli, Agnès Petit-Paitel, Étienne C. Hirsch et al. · Biochemical and Biophysical Research Communications · 1999 · 61 citations

Molecular Pharmacology, Biochemistry, Cell Permeant Inhibitor +9

Effect of S 17092, a novel prolyl endopeptidase inhibitor, on substance P and α‐melanocyte‐stimulating hormone breakdown in the rat brain

Gaëlle Bellemère, Philippe Morain, Hubert Vaudry et al. · Journal of Neurochemistry · 2003 · 60 citations

4<i>H</i>-1,2,4-Pyridothiadiazine 1,1-Dioxides and 2,3-Dihydro-4<i>H</i>-1,2,4-pyridothiadiazine 1,1-Dioxides Chemically Related to Diazoxide and Cyclothiazide as Powerful Positive Allosteric Modulators of (<i>R</i>/<i>S</i>)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors:  Design, Synthesis, Pharmacology, and Structure−Activity Relationships

Bernard Pirotte, Tchao Podona, Ousmane Diouf et al. · Journal of Medicinal Chemistry · 1998 · 60 citations

Ampa Receptor Modulator, Pharmacotherapy, Chemistry +19