Enhancement of Attentional Performance by Selective Stimulation of α4β2* nAChRs: Underlying Cholinergic Mechanisms

William M. Howe, Jinzhao Ji, Vinay Parikh, +4

Neuropsychopharmacology

Synaptic TransmissionNeurotransmitterNeurotransmissionSelective StimulationAttention +14

Dissociating β-Amyloid from α7 Nicotinic Acetylcholine Receptor by a Novel Therapeutic Agent, S 24795, Normalizes α7 Nicotinic Acetylcholine and NMDA Receptor Function in Alzheimer's Disease Brain

Hoau-Yan Wang, Andres Stucky, Jingjing Liu, +3

Journal of Neuroscience

Electrophysiological Perspectives on the Therapeutic Use of Nicotinic Acetylcholine Receptor Partial Agonists

Roger L. Papke, Caryn Trocme‐Thibierge, Daniela Guendisch, +2

Journal of Pharmacology and Experimental Therapeutics

The partial α7 nicotine acetylcholine receptor agonist S 24795 enhances long-term potentiation at CA3-CA1 synapses in the adult mouse hippocampus

Laura Lagostena, Caryn Trocme‐Thibierge, Philippe Morain, +1

Neuropharmacology

Ca3-ca1 SynapsesSynaptic PlasticityMolecular NeuroscienceNeurophysiologyCellular Neuroscience +13

S 24795 Limits β-Amyloid–α7 Nicotinic Receptor Interaction and Reduces Alzheimer's Disease-Like Pathologies

Hoau-Yan Wang, Kalindi Bakshi, Changpeng Shen, +3

Biological Psychiatry

Molecular PharmacologyNeurodegenerative DiseasesAlzheimer's DiseaseMolecular NeuroscienceMedicine +11

Comparative effects of the α7 nicotinic partial agonist, S 24795, and the cholinesterase inhibitor, donepezil, against aging-related deficits in declarative and working memory in mice

Aline Marighetto, Stéphane Valério, Aline Desmedt, +3

Psychopharmacology

AgingCognitive PerformanceMedicineMemory LossAging-related Deficits +10

Improvement of contextual memory by S 24795 in aged mice: comparison with memantine

Daniel Béracochéa, Aurélie Boucard, Caryn Trocme‐Thibierge, +1

Psychopharmacology

Contextual MemoryCognitive ScienceMemory SystemMnemonicMemory Loss +5

Partial agonist and neuromodulatory activity of S 24795 for alpha7 nAChR responses of hippocampal interneurons

Gretchen Y. López‐Hernández, Andon N. Placzek, Jeffrey S. Thinschmidt, +4

Neuropharmacology

Synaptic TransmissionNeuromodulatory ActivityNeuropharmacologyS 24795Neuroscience +7

Positive modulation of α7 nAChR responses in rat hippocampal interneurons to full agonists and the α7-selective partial agonists, 4OH-GTS-21 and S 24795

Gretchen Y. López‐Hernández, Jeffrey S. Thinschmidt, Philippe Morain, +4

Neuropharmacology

Synaptic PlasticityPositive ModulationCellular NeuroscienceSynaptic TransmissionPhysiology +10

RETRACTED ARTICLE: Increased Aβ42-α7-like nicotinic acetylcholine receptor complex level in lymphocytes is associated with apolipoprotein E4-driven Alzheimer’s disease pathogenesis

Hoau-Yan Wang, Caryn Trocme‐Thibierge, Andres Stucky, +12

Alzheimer s Research & Therapy