John C.R. Randle - Concepedia

Author

John C.R. Randle

Also Known As

J C Randle, J. C. R. RANDLE, J. C. Randle, J. Randle, J.C.R. Randle, John C R Randle, John C. R. Randle, John C. Randle, John C.R Randle, John C.R. Randle

Publications

2.3K

Citations

H-Index

Concepts

All Affiliations

Servier (France)Vertex Pharmaceuticals (United States)Montreal General Hospital Sanofi (France)McGill University

About

John C.R. Randle is an author at Servier (France) specializing in medicine, pharmacology, and physiology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	16	19	963
2	Social Sciences	7	7	558
3	Natural Sciences	2	2	35
4	Engineering	1	1	71
5	Health Sciences	1	1	20

John C.R. Randle

Publications

2.1K

Citations

H-Index

Page 1

	Year	Citations
(S)-1-((S)-2-{[1-(4-Amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2 R,3 S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an Orally Available Selective Interleukin (IL)-Converting Enzyme/Caspase-1 Inhibitor, Exhibits Potent Anti-Inflammatory Activities by Inhibiting the Release of IL-1β and IL-18 Woods Wannamaker, Robert M. D. Davies, Mark Namchuk, Journal of Pharmacology and Experimental Therapeutics	2007	309
IL-Converting Enzyme/Caspase-1 Inhibitor VX-765 Blocks the Hypersensitive Response to an Inflammatory Stimulus in Monocytes from Familial Cold Autoinflammatory Syndrome Patients Jeffrey H. Stack, Kevin Beaumont, Paul D. Larsen, The Journal of Immunology	2005	187
Inactivation of Caspase‐1 in Rodent Brain: A Novel Anticonvulsive Strategy Teresa Ravizza, Sian‐Marie Lucas, Silvia Balosso, Epilepsia	2006	173
Opposing α- and β-adrenergic mechanisms mediate dose-dependent actions of noradrenaline on supraoptic vasopressin neurones in vivo Trevor A. Day, John C.R. Randle, Leo P. Renaud Brain Research Dose-dependent ActionsNeurophysiologyβ-Adrenergic MechanismsSynaptic TransmissionPhysiology	1985	142
Calcium-dependent potassium conductance in rat supraoptic nucleus neurosecretory neurons Charles W. Bourque, John C.R. Randle, Leo P. Renaud Journal of Neurophysiology Synaptic TransmissionNeurotransmitterCalcium-dependent Potassium ConductanceNeurotransmissionSocial Sciences	1985	127
Actions of gamma‐aminobutyric acid on rat supraoptic nucleus neurosecretory neurones in vitro. John C.R. Randle, Leo P. Renaud The Journal of Physiology	1987	97
Alpha 1-adrenergic receptor activation depolarizes rat supraoptic neurosecretory neurons in vitro John C.R. Randle, Charles W. Bourque, Leo P. Renaud American Journal of Physiology-Regulatory, Integrative and Comparative Physiology Membrane ResistanceSynaptic TransmissionAnesthetic MechanismNeurotransmissionSocial Sciences	1986	92
Characterization of spontaneous and evoked inhibitory postsynaptic potentials in rat supraoptic neurosecretory neurons in vitro John C.R. Randle, Charles W. Bourque, Leo P. Renaud Journal of Neurophysiology Synaptic TransmissionNeurotransmitterNeuromodulation TherapiesNeurotransmissionSocial Sciences	1986	76
Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X<sub>7</sub> receptor‐mediated IL‐1β release Liliana Bernardino, Silvia Balosso, Teresa Ravizza, Journal of Neurochemistry	2008	74
α1-Adrenergic receptor activation releases vasopressin and oxytocin from perfused rat hypothalamic explants John C.R. Randle, M F Mazurek, D. Kneifel, Neuroscience Letters Molecular Pharmacologyα1-Adrenergic Receptor ActivationHypothalamusSodium HomeostasisMedicine	1986	73

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