Audrey M. Davies

Discovery of 5-Chloro-<i>N</i>²-[(1<i>S</i>)-1-(5-fluoropyrimidin-2-yl)ethyl]-<i>N</i>⁴-(5-methyl-1<i>H</i>-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a Novel Inhibitor of the Jak/Stat Pathway

Stephanos Ioannidis, Michelle L. Lamb, Tao Wang et al. · Journal of Medicinal Chemistry · 2010 · 123 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Effects of the JAK2 Inhibitor, AZ960, on Pim/BAD/BCL-xL Survival Signaling in the Human JAK2 V617F Cell Line SET-2

Joseph M. Gozgit, Geraldine Bebernitz, Pankaj Patil et al. · Journal of Biological Chemistry · 2008 · 101 citations · Full text

Life Sciences, Cell Biology, Pharmacotherapy +13

Identification of 4-Aminopyrazolylpyrimidines as Potent Inhibitors of Trk Kinases

Tao Wang, Michelle L. Lamb, David A. Scott et al. · Journal of Medicinal Chemistry · 2008 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Discovery of Disubstituted Imidazo[4,5-<i>b</i>]pyridines and Purines as Potent TrkA Inhibitors

Tao Wang, Michelle L. Lamb, Audrey M. Davies et al. · ACS Medicinal Chemistry Letters · 2012 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structure–activity studies of a series of dipyrazolo[3,4-b:3′,4′-d]pyridin-3-ones binding to the immune regulatory protein B7.1

Neal J. Green, Jason Xiang, Jing Chen et al. · Bioorganic & Medicinal Chemistry · 2003 · 45 citations

Life Sciences, Immunology, Medicinal Chemistry +12