Giovanna R. Mallucci

Depleting Neuronal PrP in Prion Infection Prevents Disease and Reverses Spongiosis

Giovanna R. Mallucci, Andrew Dickinson, Jacqueline M. Linehan et al. · Science · 2003 · 751 citations

Creutzfeldt-jakob Disease, Immunology, Social Sciences +16

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

Julie A. Moreno, Helois Radford, Diego Peretti et al. · Nature · 2012 · 596 citations · Full text

Neurodegenerative Diseases, Transcriptional Regulation, Molecular Neuroscience +8

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

Julie A. Moreno, Mark Halliday, Colin Molloy et al. · Science Translational Medicine · 2013 · 566 citations

Creutzfeldt-jakob Disease, Immunology, Cell Death +18

Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration

Giovanna R. Mallucci, Stéphanie Ratté, Emmanuel A. Asante et al. · The EMBO Journal · 2002 · 379 citations · Full text

Neurodegenerative Diseases, Developmental Biology, Neurophysiology +10

Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity

M.S. Halliday, Helois Radford, Yusuke Sekine et al. · Cell Death and Disease · 2015 · 369 citations · Full text