Kazuko Takami

A conformational restriction approach to the development of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease

Narihiro Toda, Keiko Tago, Shinji Marumoto et al. · Bioorganic & Medicinal Chemistry · 2003 · 89 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design and Synthesis of Dual Inhibitors of Acetylcholinesterase and Serotonin Transporter Targeting Potential Agents for Alzheimer's Disease

Hiroshi Kogen, Narihiro Toda, Keiko Tago et al. · Organic Letters · 2002 · 71 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Pharmacological Characterization of RS-1259, an Orally Active Dual Inhibitor of Acetylcholinesterase and Serotonin Transporter, in Rodents: Possible Treatment of Alzheimer’s Disease

Yasuyuki Abe, Atsushi Aoyagi, Takao Hara et al. · Journal of Pharmacological Sciences · 2003 · 49 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Stereospecific Construction of Contiguous Quaternary and Tertiary Stereocenters by Rearrangement from Indoline‐2‐methanol to 2,2,3‐Trisubstituted Tetrahydroquinoline: Application to an Efficient Total Synthesis of Natural Virantmycin

Mayuko Ori, Narihiro Toda, Kazuko Takami et al. · Angewandte Chemie International Edition · 2003 · 46 citations

Pharmacy, Chemistry, Medicinal Chemistry +11

Design, synthesis and structure–Activity relationships of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease

Narihiro Toda, Keiko Tago, Shinji Marumoto et al. · Bioorganic & Medicinal Chemistry · 2003 · 39 citations

Medicine, Medicinal Chemistry, Pharmacology +17