Concepedia

Victoriano Tamez

VT

Statistics

Publications

7

Citations

541

H-Index

7

Active since

2013

Affiliations

Novartis (United States)(Current)

Novartis (Switzerland)

Genomics Institute of the Novartis Research Foundation

Victoriano Tamez is an author at Novartis (United States) specializing in drug discovery, medicinal chemistry, and drug design.

Publications per year

2013–2020

7

Publications

7

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer

Matthew J. LaMarche, Michael Acker, Andreea Argintaru et al. · Journal of Medicinal Chemistry · 2020 · 222 citations · Full text

, , +17

6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

Patrick Sarver, Michael Acker, Jeffrey T. Bagdanoff et al. · Journal of Medicinal Chemistry · 2019 · 86 citations · Full text

, , +14

Identification of <i>N</i>-(4-((1<i>R</i>,3<i>S</i>,5<i>S</i>)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies

Matthew T. Burger, Gisele Nishiguchi, Wooseok Han et al. · Journal of Medicinal Chemistry · 2015 · 76 citations · Full text

, , +13

Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors

Matthew T. Burger, Wooseok Han, Jiong Lan et al. · ACS Medicinal Chemistry Letters · 2013 · 53 citations · Full text

, , +13

Design and Discovery of <i>N</i>-(2-Methyl-5′-morpholino-6′-((tetrahydro-2<i>H</i>-pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers

Gisele Nishiguchi, Alice Rico, Huw R. Tanner et al. · Journal of Medicinal Chemistry · 2017 · 44 citations · Full text

, , +15

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