Concepedia

Patrick Sarver

PS

8

Publications

1.5K

Citations

8

H-Index

2018

Active since

Affiliations

Princeton University(Current)

Novartis (United States)

Merck & Co., Inc., Rahway, NJ, USA (United States)

Patrick Sarver is an author at Princeton University specializing in natural sciences, drug discovery, and medicinal chemistry.

Top concepts

MedicineChemistryPharmacologyDrug DiscoveryNatural SciencesOrganic ChemistryMedicinal ChemistryCatalysisEngineeringBiochemistry

Publications per year

2018–2023

8

Publications

8

Direct arylation of strong aliphatic C–H bonds

Ian B. Perry, Thomas F. Brewer, Patrick Sarver et al. · Nature · 2018 · 544 citations · Full text

Hydrogen Bond, Organic Chemistry, Chemistry +2

The merger of decatungstate and copper catalysis to enable aliphatic C(sp3)–H trifluoromethylation

Patrick Sarver, Vlad Bacauanu, Danielle M. Schultz et al. · Nature Chemistry · 2020 · 342 citations

Chemical Engineering, Engineering, Aliphatic C +6

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer

Matthew J. LaMarche, Michael Acker, Andreea Argintaru et al. · Journal of Medicinal Chemistry · 2020 · 207 citations · Full text

Decatungstate-Catalyzed C(<i>sp</i><sup>3</sup>)–H Sulfinylation: Rapid Access to Diverse Organosulfur Functionality

Patrick Sarver, Noah B. Bissonnette, David W. C. MacMillan · Journal of the American Chemical Society · 2021 · 142 citations · Full text

6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

Patrick Sarver, Michael Acker, Jeffrey T. Bagdanoff et al. · Journal of Medicinal Chemistry · 2019 · 85 citations · Full text

Medicinal Chemistry, Allosteric Shp2 Inhibitors, Drug Target +15

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