Edward E. S. Nieuwenhuis

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

Meritxell Huch, Helmuth Gehart, Ruben van Boxtel et al. · Cell · 2014 · 1.6K citations · Full text

Enormous Replication Potential, Adult Stem Cell, Expanded Cells +28

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

Arthur Kaser, Ann–Hwee Lee, André Franke et al. · Cell · 2008 · 1.4K citations · Full text

Inflammation, Functional Gastrointestinal Disorder, Intestinal Inflammation +9

Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

Gerald Schwank, Bon‐Kyoung Koo, Valentina Sasselli et al. · Cell stem cell · 2013 · 1.4K citations · Full text

Fibrosis, Cystic Fibrosis Patients, Functional Repair +7

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

Caroline A. Lindemans, Marco Calafiore, Anna Mertelsmann et al. · Nature · 2015 · 1.1K citations · Full text

Inflammation, Cytokine, Mucosal Immunology +7

A functional CFTR assay using primary cystic fibrosis intestinal organoids

Johanna F. Dekkers, Caroline L. Wiegerinck, Hugo R. de Jonge et al. · Nature Medicine · 2013 · 977 citations

Inflammation, Fibrosis, Immunology +6