Dennis T. Takata

Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

David Payne, William H. Miller, Valerie Berry et al. · Antimicrobial Agents and Chemotherapy · 2002 · 165 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Identification of 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3<i>S</i>)-3-piperidinylmethyl]oxy}-1<i>H</i>-imidazo[4,5-<i>c</i>]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a Novel Inhibitor of AKT Kinase

Dirk A. Heerding, Nelson Rhodes, Jack D. Leber et al. · Journal of Medicinal Chemistry · 2008 · 155 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)

Dirk A. Heerding, George Chan, Walter E. DeWolf et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 124 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Potent, Selective, Orally Active 3-Oxo-1,4-benzodiazepine GPIIb/IIIa Integrin Antagonists

James M. Samanen, Fadia E. Ali, Linda S. Barton et al. · Journal of Medicinal Chemistry · 1996 · 72 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Combinatorial chemistry. Use of an intramolecular ruthenium catalyzed olefin/alkyne metathesis reaction in tandem with a Diels-Alder cycloaddition reaction to construct functionalized hexahydroisoindoles

Dirk A. Heerding, Dennis T. Takata, Chet Kwon et al. · Tetrahedron Letters · 1998 · 51 citations

Natural Sciences, Chemistry, Catalysis +16