Jack D. Leber

Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Nelson Rhodes, Dirk A. Heerding, Derek R. Duckett et al. · Cancer Research · 2008 · 298 citations · Full text

Medicine, Oncology, Pharmacology +17

SB 209670, a rationally designed potent nonpeptide endothelin receptor antagonist.

Eliot H. Ohlstein, P Nambi, Stephen A. Douglas et al. · Proceedings of the National Academy of Sciences · 1994 · 163 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Identification of 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3<i>S</i>)-3-piperidinylmethyl]oxy}-1<i>H</i>-imidazo[4,5-<i>c</i>]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a Novel Inhibitor of AKT Kinase

Dirk A. Heerding, Nelson Rhodes, Jack D. Leber et al. · Journal of Medicinal Chemistry · 2008 · 155 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

1,3-Diarylindan-2-carboxylic Acids, Potent and Selective Non-Peptide Endothelin Receptor Antagonists

John D. Elliott, M. Amparo Lago, Russell D. Cousins et al. · Journal of Medicinal Chemistry · 1994 · 127 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Discovery of Aminofurazan-azabenzimidazoles as Inhibitors of Rho-Kinase with High Kinase Selectivity and Antihypertensive Activity

Robert A. Stavenger, Haifeng Cui, Sarah E. Dowdell et al. · Journal of Medicinal Chemistry · 2006 · 71 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17