Allison Rohner

Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity

Timothy S. Fisher, Cris Kamperschroer, Theodore Oliphant et al. · Cancer Immunology Immunotherapy · 2012 · 162 citations · Full text

Tumor Biology, Cancer Immunosurveillance, T-regulatory Cell +7

Effective Targeting of Hedgehog Signaling in a Medulloblastoma Model with PF-5274857, a Potent and Selective Smoothened Antagonist That Penetrates the Blood–Brain Barrier

Allison Rohner, Mary E. Spilker, Justine L. Lam et al. · Molecular Cancer Therapeutics · 2011 · 51 citations

Cancer Biology, Tumor Biology, Selective Smoothened Antagonist +17

A CD3-bispecific molecule targeting P-cadherin demonstrates T cell-mediated regression of established solid tumors in mice

Timothy S. Fisher, Andrea T. Hooper, Justin Lucas et al. · Cancer Immunology Immunotherapy · 2017 · 40 citations · Full text

Cancer Immunosurveillance, Solid Tumors, Cell Signaling +12

Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1

Rebecca A. Gallego, Louise Bernier, Hui Chen et al. · Journal of Medicinal Chemistry · 2023 · 33 citations · Full text

Discovery of PF-07265028, A Selective Small Molecule Inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) for the Treatment of Cancer

Rebecca A. Gallego, Sujin Cho-Schultz, Matthew Del Bel et al. · Journal of Medicinal Chemistry · 2024 · 16 citations