Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus

Theodore Oliphant, Michael J. Engle, Grant E. Nybakken, +11

Nature Medicine

Therapeutic PotentialImmunologyAntiviral ResponseVirologyAntibody Screening +6

Structural basis of West Nile virus neutralization by a therapeutic antibody

Grant E. Nybakken, Theodore Oliphant, Syd Johnson, +3

Nature

Virus StructureImmunologyAntiviral ResponseAntiviral Drug DevelopmentVirology +6

The Stoichiometry of Antibody-Mediated Neutralization and Enhancement of West Nile Virus Infection

Theodore C. Pierson, Qing Xu, Steevenson Nelson, +4

Cell Host & Microbe

PathogenesisImmunologyViral PathogenesisAntibody-mediated NeutralizationVirology +6

Antibody Recognition and Neutralization Determinants on Domains I and II of West Nile Virus Envelope Protein

Theodore Oliphant, Grant E. Nybakken, Michael J. Engle, +9

Journal of Virology

ImmunologyViral PathogenesisMolecular BiologyViral Structural ProteinImmunotherapy +14

Type- and Subcomplex-Specific Neutralizing Antibodies against Domain III of Dengue Virus Type 2 Envelope Protein Recognize Adjacent Epitopes

Soila Sukupolvi-Petty, S. Kyle Austin, Whitney E. Purtha, +8

Journal of Virology

Maturation of West Nile Virus Modulates Sensitivity to Antibody-Mediated Neutralization

Steevenson Nelson, Christiane A. Jost, Qinq Xu, +8

PLoS Pathogens

VaccinationMolecular VirologyVirion MaturationComplete MaturationPathogenesis +12

Induction of Epitope-Specific Neutralizing Antibodies against West Nile Virus

Theodore Oliphant, Grant E. Nybakken, S. Kyle Austin, +7

Journal of Virology

Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity

Timothy S. Fisher, Cris Kamperschroer, Theodore Oliphant, +10

Cancer Immunology Immunotherapy

Tumor BiologyCancer ImmunosurveillanceT-regulatory CellImmunologyImmune Checkpoint Inhibitor +5

Complement Activation Is Required for Induction of a Protective Antibody Response against West Nile Virus Infection

Erin Mehlhop, Kevin Whitby, Theodore Oliphant, +3

Journal of Virology

Humoral ResponseImmunologyViral PathogenesisInnate Immune SystemInnate Immunity +16

Protective and Therapeutic Capacity of Human Single-Chain Fv-Fc Fusion Proteins against West Nile Virus

L. Hannah Gould, Jianhua Sui, Harald G. Foellmer, +13

Journal of Virology

Viral ReplicationViral PathogenesisImmunologyViral Structural ProteinImmunotherapy +14