Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus

Theodore Oliphant, Michael J. Engle, Grant E. Nybakken, +11

Nature Medicine

Therapeutic PotentialImmunologyAntiviral ResponseVirologyAntibody Screening +6

Structural basis of West Nile virus neutralization by a therapeutic antibody

Grant E. Nybakken, Theodore Oliphant, Syd Johnson, +3

Nature

Virus StructureImmunologyAntiviral ResponseAntiviral Drug DevelopmentVirology +6

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins

Shee‐Mei Lok, V.A. Kostyuchenko, Grant E. Nybakken, +10

Nature Structural & Molecular Biology

Virus StructureMolecular VirologyImmunologyGlycobiologyVirology +7

The Stoichiometry of Antibody-Mediated Neutralization and Enhancement of West Nile Virus Infection

Theodore C. Pierson, Qing Xu, Steevenson Nelson, +4

Cell Host & Microbe

PathogenesisImmunologyViral PathogenesisAntibody-mediated NeutralizationVirology +6

Antibody Recognition and Neutralization Determinants on Domains I and II of West Nile Virus Envelope Protein

Theodore Oliphant, Grant E. Nybakken, Michael J. Engle, +9

Journal of Virology

ImmunologyViral PathogenesisMolecular BiologyViral Structural ProteinImmunotherapy +14

Crystal Structure of the West Nile Virus Envelope Glycoprotein

Grant E. Nybakken, Christopher A. Nelson, Beverly R. Chen, +2

Journal of Virology

Virus StructureDimeric ECrystal StructureViral ReplicationMolecular Virology +11

Type- and Subcomplex-Specific Neutralizing Antibodies against Domain III of Dengue Virus Type 2 Envelope Protein Recognize Adjacent Epitopes

Soila Sukupolvi-Petty, S. Kyle Austin, Whitney E. Purtha, +8

Journal of Virology

West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H

Kyung Min Chung, M. Kathryn Liszewski, Grant E. Nybakken, +5

Proceedings of the National Academy of Sciences

Complement SystemMolecular VirologyAllergyDecreased Complement ActivationNeurovirology +12

Antibodies against West Nile Virus Nonstructural Protein NS1 Prevent Lethal Infection through Fc γ Receptor-Dependent and -Independent Mechanisms

Kyung Min Chung, Grant E. Nybakken, Bruce S. Thompson, +4

Journal of Virology

Viral PathogenesisImmunologyViral Structural ProteinImmune SystemFc γ Receptor-dependent +16

Structural basis for the preferential recognition of immature flaviviruses by a fusion‐loop antibody

Mickaël V. Cherrier, Bärbel Kaufmann, Grant E. Nybakken, +11

The EMBO Journal