Concepedia

Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity

Timothy S. Fisher, Cris Kamperschroer, Theodore Oliphant, Victoria Love, Paul D. Lira, Régis Doyonnas, Simon Bergqvist, Sangita M. Baxi, Allison Rohner, A C Shen,

Cancer Immunology Immunotherapy · 2012 · 163 citations · 36 references

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36

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

David L. Porter, Bruce L. Levine, Michael Kalos et al. · New England Journal of Medicine · 2011 · 3.5K citations · Full text

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T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia

Michael Kalos, Bruce L. Levine, David L. Porter et al. · Science Translational Medicine · 2011 · 2.4K citations · Full text

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CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans

Gregory L. Beatty, E. Gabriela Chiorean, Matthew P. Fishman et al. · Science · 2011 · 1.6K citations

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Humanized mice in translational biomedical research

Leonard D. Shultz, Fumihiko Ishikawa, Dale L. Greiner · Nature reviews. Immunology · 2007 · 1.3K citations

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Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

Michael C. Milone, Jonathan D. Fish, Carmine Carpenito et al. · Molecular Therapy · 2009 · 1.2K citations · Full text

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