Craig Swearingen

Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease

Daniel P. Becker, Thomas E. Barta, Louis J. Bedell et al. · Journal of Medicinal Chemistry · 2010 · 100 citations · Full text

Medicine, Oncology, Pharmacology +8

Synthesis and Structure−Activity Relationships of β- and α-Piperidine Sulfone Hydroxamic Acid Matrix Metalloproteinase Inhibitors with Oral Antitumor Efficacy

Daniel P. Becker, Clara I. Villamil, Thomas E. Barta et al. · Journal of Medicinal Chemistry · 2005 · 65 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design

Spencer B. Jones, Lance A. Pfeifer, Thomas J. Bleisch et al. · ACS Medicinal Chemistry Letters · 2016 · 47 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Development of a novel clinical biomarker assay to detect and quantify aggrecanase-generated aggrecan fragments in human synovial fluid, serum and urine

Craig Swearingen, John W. Carpenter, Robert W. Siegel et al. · Osteoarthritis and Cartilage · 2010 · 38 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1

Daniel P. Becker, Thomas E. Barta, Louis J. Bedell et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +5