Louis J. Bedell

Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease

Daniel P. Becker, Thomas E. Barta, Louis J. Bedell et al. · Journal of Medicinal Chemistry · 2010 · 97 citations · Full text

Spare Mmp-1, Pharmacotherapy, Pharmaceutical Chemistry +17

Synthesis and Biological Evaluation of Novel 2,4-Diaminoquinazoline Derivatives as <i>SMN2</i> Promoter Activators for the Potential Treatment of Spinal Muscular Atrophy

John B. Thurmond, Matthew E.R. Butchbach, Marty Palomo et al. · Journal of Medicinal Chemistry · 2008 · 92 citations · Full text

Synthesis and Structure−Activity Relationships of β- and α-Piperidine Sulfone Hydroxamic Acid Matrix Metalloproteinase Inhibitors with Oral Antitumor Efficacy

Daniel P. Becker, Clara I. Villamil, Thomas E. Barta et al. · Journal of Medicinal Chemistry · 2005 · 64 citations · Full text

Pharmaceutical Science, Breast Oncology, Immunology +23

α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1

Daniel P. Becker, Thomas E. Barta, Louis J. Bedell et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 37 citations · Full text

Medicinal Chemistry, Medicine, Potent Mmp-13 Inhibitors +6

Synthesis and activity of selective MMP inhibitors with an aryl backbone

Thomas E. Barta, Daniel P. Becker, Louis J. Bedell et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 28 citations · Full text

Medicinal Chemistry, Selective Mmp Inhibitors, Biochemistry +8