Lloyd King

High-Level Periplasmic Expression in Escherichia coli Using a Eukaryotic Signal Peptide: Importance of Codon Usage at the 5′ End of the Coding Sequence

David P. Humphreys, Mukesh Sehdev, Andrew P. Chapman et al. · Protein Expression and Purification · 2000 · 67 citations

Codon Usage, Protein Expression, Natural Sciences +10

A plasmid system for optimization of Fab′ production in Escherichia coli: importance of balance of heavy chain and light chain synthesis

David P. Humphreys, Bruce Carrington, Leigh C. Bowering et al. · Protein Expression and Purification · 2002 · 52 citations

Fab′ Production, Biosynthesis, Biomanufacturing +14

2016 White Paper on Recent Issues in Bioanalysis: Focus on Biomarker Assay Validation (BAV) (Part 1 – Small Molecules, Peptides and Small Molecule Biomarkers by LCMS)

Eric Yang, Jan Welink, Stephanie Cape et al. · Bioanalysis · 2016 · 48 citations · Full text

Discovery of 4-azaindoles as novel inhibitors of c-Met kinase

John Porter, Simon Lumb, Richard J. Franklin et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 38 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, C-met Kinase +4

F(ab′)2 molecules made from Escherichia coli produced Fab′ with hinge sequences conferring increased serum survival in an animal model

David P. Humphreys, Olivia M. Vetterlein, Andrew P. Chapman et al. · Journal of Immunological Methods · 1998 · 34 citations

Protein Expression, Biochemistry, Natural Sciences +11