Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3

Elaine Huston, Simon Lumb, Annette Russell, +7

Biochemical Journal

The inhibition of antigen‐induced eosinophilia and bronchoconstriction by CDP840, a novel stereo‐selective inhibitor of phosphodiesterase type 4

B. Hughes, D. Howat, H. Lisle, +22

British Journal of Pharmacology

InflammationMolecular PharmacologyPotent Pde 4Pleural EosinophiliaAllergy +10

Altered Epithelial Gene Expression in Peripheral Airways of Severe Asthma

Akul Singhania, Hitasha Rupani, Nivenka Jayasekera, +6

PLoS ONE

InflammationAsthmaGene Expression ResponseInflammatory Lung DiseaseAllergy +13

Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase

John Porter, Simon Lumb, Fabien Lecomte, +11

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryMedicinal ChemistryC-met KinaseNovel SeriesBiochemistry +9

Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling

Ralph Adams, Rebecca J. Burnley, Chiara R. Valenzano, +17

Scientific Reports

Discovery of 4-azaindoles as novel inhibitors of c-Met kinase

John Porter, Simon Lumb, Richard J. Franklin, +14

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryMedicinal ChemistryC-met KinaseMedicineRational Drug Design +2

Spontaneous Extracellular Matrix Accumulation in a Human in vitro Model of Renal Fibrosis Is Mediated by αV Integrins

Hélène Bon, Paul Hales, Simon Lumb, +4

˜The œNephron journals/Nephron journals

Chromosomal Deletions in Melibiose-negative Isolates of Streptococcus mutans

I. Ushiro, Simon Lumb, Joseph Aduse‐Opoku, +2

Journal of Dental Research

Molecular Cloning and Expression of a Human Phosphodiesterase 4C

Raymond J. Owens, Simon Lumb, Karen Rees‐Milton, +6

Cellular Signalling

Protein ExpressionNatural SciencesMolecular BiologyProtein EngineeringMolecular Cloning +2

CDP840

Maria de Jesus Perry, James P. O’Connell, Christoph Walker, +14

Cell Biochemistry and Biophysics