Concepedia

Joseph Nacson

JN

6

Publications

553

Citations

6

H-Index

2016

Active since

Affiliations

Fox Chase Cancer Center(Current)

Temple University

UNC Lineberger Comprehensive Cancer Center

National Cancer Institute

University of North Carolina at Chapel Hill

Joseph Nacson is an author at Fox Chase Cancer Center specializing in genetic engineering, medicine, and genetics.

Top concepts

Publications per year

2016–2023

6

Publications

6

The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin

Yifan Wang, Andrea J. Bernhardy, Cristina Cruz et al. · Cancer Research · 2016 · 267 citations · Full text

BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance

Joseph Nacson, John J. Krais, Andrea J. Bernhardy et al. · Cell Reports · 2018 · 96 citations · Full text

BRCA1 intronic Alu elements drive gene rearrangements and PARP inhibitor resistance

Yifan Wang, Andrea J. Bernhardy, Joseph Nacson et al. · Nature Communications · 2019 · 60 citations · Full text

BRCA1 Mutational Complementation Induces Synthetic Viability

Joseph Nacson, Daniela Di Marcantonio, Yifan Wang et al. · Molecular Cell · 2020 · 59 citations · Full text

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<i>TET2</i> and <i>DNMT3A</i> Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors

Silvia Maifrede, Bac Viet Le, Margaret Nieborowska-Skorska et al. · Cancer Research · 2021 · 49 citations · Full text

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