Concepedia

John J. Krais

JJ

20

Publications

1.5K

Citations

16

H-Index

2013

Active since

Affiliations

Fox Chase Cancer Center(Current)

Temple University

University of Oklahoma

University of Washington

University of Oklahoma Health Sciences Center

John J. Krais is an author at Fox Chase Cancer Center specializing in medicine, cell biology, and molecular biology.

Top concepts

MedicineCell BiologyMolecular BiologyChromatinDna ReplicationNatural SciencesGenome InstabilityCell CycleBreast CancerDrug Discovery

Publications per year

2013–2024

20

Publications

20

Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency

Ke Cong, Min Peng, Arne Nedergaard Kousholt et al. · Molecular Cell · 2021 · 298 citations · Full text

Genome Instability, Natural Sciences, Key Determinant +8

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

Olga Kondrashova, Monique Topp, Ksenija Nesic et al. · Nature Communications · 2018 · 277 citations · Full text

The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin

Yifan Wang, Andrea J. Bernhardy, Cristina Cruz et al. · Cancer Research · 2016 · 267 citations · Full text

RING domain–deficient BRCA1 promotes PARP inhibitor and platinum resistance

Yifan Wang, John J. Krais, Andrea J. Bernhardy et al. · Journal of Clinical Investigation · 2016 · 104 citations · Full text

BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance

Joseph Nacson, John J. Krais, Andrea J. Bernhardy et al. · Cell Reports · 2018 · 96 citations · Full text

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