Silvia Maifrede

Ruxolitinib-induced defects in DNA repair cause sensitivity to PARP inhibitors in myeloproliferative neoplasms

Margaret Nieborowska-Skorska, Silvia Maifrede, Yashodhara Dasgupta et al. · Blood · 2017 · 75 citations · Full text

Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells

Margaret Nieborowska-Skorska, Katherine Sullivan, Yashodhara Dasgupta et al. · Journal of Clinical Investigation · 2017 · 74 citations · Full text

Mixed-phenotype Acute Leukemia, Cell Death, Leukemia Cells +18

Tyrosine kinase inhibitor–induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors

Silvia Maifrede, Margaret Nieborowska-Skorska, Katherine Sullivan-Reed et al. · Blood · 2018 · 73 citations · Full text

<i>TET2</i> and <i>DNMT3A</i> Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors

Silvia Maifrede, Bac Viet Le, Margaret Nieborowska-Skorska et al. · Cancer Research · 2021 · 49 citations · Full text

MLL-AF9 leukemias are sensitive to PARP1 inhibitors combined with cytotoxic drugs

Silvia Maifrede, Esteban Martı́nez, Margaret Nieborowska-Skorska et al. · Blood Advances · 2017 · 33 citations · Full text

Hematological Malignancy, Mll-af9 Leukemias.parp1 Inhibitors, Oncology +14