Jarrett Adams

Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

Zachary Steinhart, Zvezdan Pavlovic, Megha Chandrashekhar et al. · Nature Medicine · 2016 · 304 citations

Rnf43-mutant Pancreatic Tumors, Signaling Pathway, Genome-wide Crispr Screens +12

T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex

Jarrett Adams, Samanthi Narayanan, Baoyu Liu et al. · Immunity · 2011 · 260 citations · Full text

Signal Transduction, T-regulatory Cell, Immunology +11

CDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic Antibodies

Helena Persson, Wei Ye, Amy K. Wernimont et al. · Journal of Molecular Biology · 2012 · 162 citations · Full text

Histocompatibility, Synthetic Antibodies, Autoimmune Disease +12

Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity

Jarrett Adams, Samanthi Narayanan, Michael E. Birnbaum et al. · Nature Immunology · 2015 · 114 citations

Structural Interplay, Engineering, Protein Folding +10

Mechanism of bacterial cell-surface attachment revealed by the structure of cellulosomal type II cohesin-dockerin complex

Jarrett Adams, Gour P. Pal, Zongchao Jia et al. · Proceedings of the National Academy of Sciences · 2005 · 107 citations · Full text