γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

Pedro J. Real, Valeria Tosello, Teresa Palomero, +13

Nature Medicine

Hematological MalignancyLymphoid NeoplasiaHematologyImmunologyGlucocorticoid Resistance +5

Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

Irene Homminga, Rob Pieters, Anton W. Langerak, +21

Cancer Cell

Hematological MalignancyMixed-phenotype Acute LeukemiaImmunologyPotential OncogenesAdult T-cell Leukemia-lymphoma +2

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols

Linda Zuurbier, Irene Homminga, Valerie Calvert, +11

Leukemia

Hematological MalignancyPediatric HematologyMedicineMixed-phenotype Acute LeukemiaImmunology +7

High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology

Marieke Simonis, Petra Klous, Irene Homminga, +5

Nature Methods

ChromatinDna SequencingNatural SciencesGeneticsComplex Chromosomal Rearrangements +9

Sustained and Transient Attention in the Continuous Performance Task

Henderikus G. O. M. Smid, M.R. de Witte, Irene Homminga, +1

Journal of Clinical and Experimental Neuropsychology

NeuropsychologyBrain FunctionTransient AttentionTask AnalysisCognition +15

BRCA1 mutation carriers have a lower number of mature oocytes after ovarian stimulation for IVF/PGD

I. A. P. Derks-Smeets, Theodora C van Tilborg, Aafke P.A. van Montfoort, +14

Journal of Assisted Reproduction and Genetics

Presence of bile acids in human follicular fluid and their relation with embryo development in modified natural cycle IVF

Roland Nagy, Aafke P.A. van Montfoort, Arne Dikkers, +5

Human Reproduction

In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia

Irene Homminga, C. Michel Zwaan, Chantal Y. Manz, +6

Blood

Cooperative genetic defects in TLX3 rearranged pediatric T-ALL

Pieter Van Vlierberghe, Irene Homminga, Linda Zuurbier, +6

Leukemia

Developmental AnomalyGenetic DisorderGeneticsCooperative Genetic DefectsMolecular Genetics +2

Characterization of a pediatric T-cell acute lymphoblastic leukemia patient with simultaneous LYL1 and LMO2 rearrangements

Irene Homminga, Maartje Vuerhard, A. W. Langerak, +3

Haematologica

Lmo2 RearrangementMixed-phenotype Acute LeukemiaGeneticsPathologyEpigenetics +16