IL-4-Induced Arginase 1 Suppresses Alloreactive T Cells in Tumor-Bearing Mice

Vincenzo Bronte, Paolo Serafini, Carmela De Santo, +9

The Journal of Immunology

γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

Pedro J. Real, Valeria Tosello, Teresa Palomero, +13

Nature Medicine

Hematological MalignancyLymphoid NeoplasiaHematologyImmunologyGlucocorticoid Resistance +5

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL

Gannie Tzoneva, Arianne Pérez-García, Zachary Carpenter, +14

Nature Medicine

Genome InstabilitySomatic VariantMedicineMolecular BiologyCancer Genetics +6

Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming

Danila Valmori, Naira E. Souleimanian, Valeria Tosello, +17

Proceedings of the National Academy of Sciences

ImmunologyImmunoeditingImmunodominanceAntigen ProcessingCd4 T Cell Responses +20

Direct Reversal of Glucocorticoid Resistance by AKT Inhibition in Acute Lymphoblastic Leukemia

Erich Piovan, Jiyang Yu, Valeria Tosello, +19

Cancer Cell

Hematological MalignancyDirect ReversalMedicineMixed-phenotype Acute LeukemiaHematology +7

DNA Hydroxymethylation Profiling Reveals that WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia

Raajit K. Rampal, Altuna Alkalin, Jozef Madžo, +31

Cell Reports

<i>ETV6</i> mutations in early immature human T cell leukemias

Pieter Van Vlierberghe, Alberto Ambesi‐Impiombato, Arianne Pérez-García, +12

The Journal of Experimental Medicine

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

Daniel Herranz, Alberto Ambesi‐Impiombato, Jessica Sudderth, +14

Nature Medicine

Hematological MalignancyAnti-notch1 TherapiesMetabolic ReprogrammingMedicineMalignant Blood Disorder +10

Rapamycin-Mediated Enrichment of T Cells with Regulatory Activity in Stimulated CD4+ T Cell Cultures Is Not Due to the Selective Expansion of Naturally Occurring Regulatory T Cells but to the Induction of Regulatory Functions in Conventional CD4+ T Cells

Danila Valmori, Valeria Tosello, Naira E. Souleimanian, +4

The Journal of Immunology

Systems BiologyAutoimmune DiseaseAdaptive Immune SystemT CellsTreg Populations +13

The TLX1 oncogene drives aneuploidy in T cell transformation

Kim De Keersmaecker, Pedro J. Real, Giusy Della Gatta, +31

Nature Medicine

T Cell TransformationCell DivisionAdult T-cell Leukemia-lymphomaMedicineCell Biology