Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents

C.A. Stein, Jens Bo Hansen, Johnathan C. Lai, +12

Nucleic Acids Research

EngineeringMolecular BiologyGene DeliveryBiomedical EngineeringCellular Physiology +18

A peripheral circulating compartment of natural naive CD4+ Tregs

Danila Valmori, Andrea Merlo, Naira E. Souleimanian, +2

Journal of Clinical Investigation

Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming

Danila Valmori, Naira E. Souleimanian, Valeria Tosello, +17

Proceedings of the National Academy of Sciences

ImmunologyImmunoeditingImmunodominanceAntigen ProcessingCd4 T Cell Responses +20

Rapamycin-Mediated Enrichment of T Cells with Regulatory Activity in Stimulated CD4+ T Cell Cultures Is Not Due to the Selective Expansion of Naturally Occurring Regulatory T Cells but to the Induction of Regulatory Functions in Conventional CD4+ T Cells

Danila Valmori, Valeria Tosello, Naira E. Souleimanian, +4

The Journal of Immunology

Systems BiologyAutoimmune DiseaseAdaptive Immune SystemT CellsTreg Populations +13

Direct Regulation of Androgen Receptor Activity by Potent CYP17 Inhibitors in Prostate Cancer Cells

Harris S. Soifer, Naira E. Souleimanian, Sijian Wu, +4

Journal of Biological Chemistry

Antisense 2′-Deoxy, 2′-Fluoroarabino Nucleic Acid (2′F-ANA) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids

Naira E. Souleimanian, Glen F. Deleavey, Harris S. Soifer, +4

Molecular Therapy — Nucleic Acids

Differential expression of CCR7 defines two distinct subsets of human memory CD4+CD25+ Tregs

Valeria Tosello, Kunle Odunsi, Naira E. Souleimanian, +5

Clinical Immunology

Systems BiologyEngineeringDifferential ExpressionCcr7 Defines TwoDistinct Subsets +3

G3139, an Anti-Bcl-2 Antisense Oligomer That Binds Heparin-Binding Growth Factors and Collagen I, Alters<i>In vitro</i>Endothelial Cell Growth and Tubular Morphogenesis

C.A. Stein, Sijian Wu, Anatoliy M. Voskresenskiy, +5

Clinical Cancer Research

Identification of two Melan-A CD4+ T cell epitopes presented by frequently expressed MHC class II alleles

Emmanuelle Godefroy, Luigi Scotto, Naira E. Souleimanian, +5

Clinical Immunology

HistocompatibilityImmunogeneticsAutoimmune DiseasePathogenesisImmunology +8

Quantitative and qualitative assessment of circulating NY-ESO-1 specific CD4+ T cells in cancer-free individuals

Danila Valmori, Naira E. Souleimanian, Charles S. Hesdorffer, +2

Clinical Immunology

Qualitative AssessmentCancer ImmunosurveillanceMedicineT-regulatory CellImmunology +7