Josephine King

Crystal Structures of the Human p56lckSH2 Domain in Complex with Two Short Phosphotyrosyl Peptides at 1.0 Å and 1.8 Å Resolution

Liang Tong, Thomas C. Warren, Josephine King et al. · Journal of Molecular Biology · 1996 · 103 citations

Short Phosphotyrosyl Peptides, Biochemistry, Natural Sciences +6

Hit-to-lead studies on benzimidazole inhibitors of ITK: Discovery of a novel class of kinase inhibitors

Roger J. Snow, Asitha Abeywardane, Scot Campbell et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 65 citations · Full text

Benzimidazole Inhibitors, Medicinal Chemistry, Drug Target +13

Itk kinase inhibitors: Initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead

K.J.M. Moriarty, Michael P. Winters, Lei Qiao et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 26 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +12

5-Aminomethyl-1H-benzimidazoles as orally active inhibitors of inducible T-cell kinase (Itk)

Michael P. Winters, Darius Robinson, Hnin Hnin Khine et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 24 citations · Full text

Drug Target, Medicine, Drug Discovery +8

2-Aminobenzimidazoles as potent ITK antagonists: de novo design of a pyrrole system targeting additional hydrogen bonding interaction

Ho Yin Lo, Jörg Bentzien, André White et al. · Tetrahedron Letters · 2008 · 19 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +9