Hnin Hnin Khine

Hit-to-lead studies on benzimidazole inhibitors of ITK: Discovery of a novel class of kinase inhibitors

Roger J. Snow, Asitha Abeywardane, Scot Campbell et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 65 citations · Full text

Benzimidazole Inhibitors, Medicinal Chemistry, Drug Target +13

5-Aminomethylbenzimidazoles as potent ITK antagonists

Doris Riether, Renée Zindell, Jennifer A. Kowalski et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 44 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Medicine +5

Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design

Brian N. Cook, Jörg Bentzien, André White et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 33 citations · Full text

Drug Design, Medicine, Receptor Tyrosine Kinase +11

Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)

K.J.M. Moriarty, Hidenori Takahashi, Steven S. Pullen et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 32 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +12

Itk kinase inhibitors: Initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead

K.J.M. Moriarty, Michael P. Winters, Lei Qiao et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 26 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +12