Asitha Abeywardane

Hit-to-lead studies on benzimidazole inhibitors of ITK: Discovery of a novel class of kinase inhibitors

Roger J. Snow, Asitha Abeywardane, Scot Campbell et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 65 citations · Full text

Benzimidazole Inhibitors, Medicinal Chemistry, Drug Target +13

The discovery of carboline analogs as potent MAPKAP-K2 inhibitors

Jiang‐Ping Wu, Ji Wang, Asitha Abeywardane et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 58 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8

Fragment-Based Discovery of Indole Inhibitors of Matrix Metalloproteinase-13

Steven J. Taylor, Asitha Abeywardane, Shuang Liang et al. · Journal of Medicinal Chemistry · 2011 · 45 citations · Full text

Matrix Metalloproteases, Molecular Biology, Indole Inhibitors +16

Synthesis, SAR, and Series Evolution of Novel Oxadiazole-Containing 5-Lipoxygenase Activating Protein Inhibitors: Discovery of 2-[4-(3-{(<i>R</i>)-1-[4-(2-Amino-pyrimidin-5-yl)-phenyl]-1-cyclopropyl-ethyl}-[1,2,4]oxadiazol-5-yl)-pyrazol-1-yl]-<i>N</i>,<i>N</i>-dimethyl-acetamide (BI 665915)

Hidenori Takahashi, Doris Riether, Alessandra Bartolozzi et al. · Journal of Medicinal Chemistry · 2015 · 35 citations · Full text

Drug Target, Pharmacotherapy, Pharmaceutical Chemistry +19

Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies

Steven J. Taylor, Anil K. Padyana, Asitha Abeywardane et al. · Journal of Medicinal Chemistry · 2013 · 30 citations · Full text

Oxindole Fragment Bound, Drug Target, Protein Assembly +18