Martina Fitzek

Vectors for efficient expression in mammalian fibroblastoid, myeloid and lymphoid cells via transfection or infection

Petra Artelt, Christine Morelle, Martina Fitzek et al. · Gene · 1988 · 169 citations

Cell Therapy, Efficient Expression, Mammalian Fibroblastoid +8

A small-molecule PI3Kα activator for cardioprotection and neuroregeneration

Grace Q. Gong, Benoît Bilanges, Ben Allsop et al. · Nature · 2023 · 136 citations · Full text

Signal Transduction, Signaling Pathway, Medicine +7

Inhibition of PI3Kβ Signaling with AZD8186 Inhibits Growth of PTEN-Deficient Breast and Prostate Tumors Alone and in Combination with Docetaxel

Urs J. Hancox, Sabina Cosulich, Lyndsey Hanson et al. · Molecular Cancer Therapeutics · 2014 · 99 citations · Full text

Discovery of (<i>R</i>)-8-(1-(3,5-Difluorophenylamino)ethyl)-<i>N</i>,<i>N</i>-dimethyl-2-morpholino-4-oxo-4<i>H</i>-chromene-6-carboxamide (AZD8186): A Potent and Selective Inhibitor of PI3Kβ and PI3Kδ for the Treatment of PTEN-Deficient Cancers

Bernard Barlaam, Sabina Cosulich, Sébastien L. Degorce et al. · Journal of Medicinal Chemistry · 2014 · 85 citations · Full text

Pten Deficient Tumors, Pharmacotherapy, Pharmaceutical Chemistry +20

Discovery of novel imidazo[1,2-a]pyridines as inhibitors of the insulin-like growth factor-1 receptor tyrosine kinase

Richard Ducray, Iain Simpson, Frédéric Jung et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 48 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +6