Benjamin Le Calvé

Lycorine, the Main Phenanthridine Amaryllidaceae Alkaloid, Exhibits Significant Antitumor Activity in Cancer Cells That Display Resistance to Proapoptotic Stimuli: An Investigation of Structure−Activity Relationship and Mechanistic Insight

Delphine Lamoral‐Theys, Anna Andolfi, Gwendoline Van Goietsenoven et al. · Journal of Medicinal Chemistry · 2009 · 256 citations

Twenty-two Lycorine-related Compounds, Mechanistic Insight, Glioma +19

Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence

Clotilde Wiel, Hélène Lallet-Daher, Delphine Gitenay et al. · Nature Communications · 2014 · 214 citations · Full text

Mitophagy, Molecular Physiology, Signal Transduction +12

Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway

Frédéric Lessard, Sebastian Igelmann, Christian Trahan et al. · Nature Cell Biology · 2018 · 165 citations

Chromatin, Rb Pathway, Cycle Arrest +5

Long-term In Vitro Treatment of Human Glioblastoma Cells with Temozolomide Increases Resistance In Vivo through Up-regulation of GLUT Transporter and Aldo-Keto Reductase Enzyme AKR1C Expression

Benjamin Le Calvé, Michał Rynkowski, Marie Le Mercier et al. · Neoplasia · 2010 · 133 citations · Full text

Vitro Treatment, Metabolic Remodeling, High-grade Gliomas +19

7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: Synthesis and in vitro biological evaluation as potential antitumor agents

Joëlle Azéma, Brigitte Guidetti, Janique Dewelle et al. · Bioorganic & Medicinal Chemistry · 2009 · 91 citations · Full text

Medicinal Chemistry, Derivatives, Biochemistry +12