Benjamin Le Calvé

Lycorine, the Main Phenanthridine Amaryllidaceae Alkaloid, Exhibits Significant Antitumor Activity in Cancer Cells That Display Resistance to Proapoptotic Stimuli: An Investigation of Structure−Activity Relationship and Mechanistic Insight

Delphine Lamoral‐Theys, Anna Andolfi, Gwendoline Van Goietsenoven et al. · Journal of Medicinal Chemistry · 2009 · 258 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence

Clotilde Wiel, Hélène Lallet-Daher, Delphine Gitenay et al. · Nature Communications · 2014 · 221 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway

Frédéric Lessard, Sebastian Igelmann, Christian Trahan et al. · Nature Cell Biology · 2018 · 180 citations

Life Sciences, Cell Biology, Molecular Biology +16

Long-term In Vitro Treatment of Human Glioblastoma Cells with Temozolomide Increases Resistance In Vivo through Up-regulation of GLUT Transporter and Aldo-Keto Reductase Enzyme AKR1C Expression

Benjamin Le Calvé, Michał Rynkowski, Marie Le Mercier et al. · Neoplasia · 2010 · 134 citations · Full text

Medicine, Oncology, Pharmacology +17

7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: Synthesis and in vitro biological evaluation as potential antitumor agents

Joëlle Azéma, Brigitte Guidetti, Janique Dewelle et al. · Bioorganic & Medicinal Chemistry · 2009 · 91 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9