Arno Velds

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

Katrien Berns, E. Marielle Hijmans, Jasper Mullenders et al. · Nature Cell Biology · 2004 · 1.1K citations · Full text

Large-scale Rnai Screen, Natural Sciences, Molecular Biology +7

Tumor Exome Analysis Reveals Neoantigen-Specific T-Cell Reactivity in an Ipilimumab-Responsive Melanoma

Nienke van Rooij, Marit M. van Buuren, Daisy Philips et al. · Journal of Clinical Oncology · 2013 · 798 citations · Full text

Immunology, Immune Regulation, Immunoediting +23

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma

Carsten Linnemann, Marit M. van Buuren, Laura Bies et al. · Nature Medicine · 2014 · 679 citations

Cancer Immunosurveillance, Human Melanoma, T-regulatory Cell +10

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human <i>BRCA1</i> -mutated basal-like breast cancer

Xiaoling Liu, Henne Holstege, Hanneke van der Gulden et al. · Proceedings of the National Academy of Sciences · 2007 · 475 citations · Full text

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

Baoxu Pang, Xiaohang Qiao, Lennert Janssen et al. · Nature Communications · 2013 · 423 citations · Full text

Histone Modifications, Molecular Biology, Drug-induced Histone Eviction +17