Henne Holstege

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Céline Bellenguez, Fahri Küçükali, Iris E. Jansen et al. · Nature Genetics · 2022 · 2.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Activation of Central Melanocortin Pathways by Fenfluramine

Lora K. Heisler, Michael A. Cowley, Laurence H. Tecott et al. · Science · 2002 · 482 citations · Full text

Medicine, Neurobiology, Pharmacology +17

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human <i>BRCA1</i> -mutated basal-like breast cancer

Xiaoling Liu, Henne Holstege, Hanneke van der Gulden et al. · Proceedings of the National Academy of Sciences · 2007 · 479 citations · Full text

Medicine, Genetics, Oncology +15

Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin

Bastiaan Evers, Rinske Drost, Eva Schut et al. · Clinical Cancer Research · 2008 · 334 citations · Full text

Medicine, Oncology, Pharmacology +16

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease

Henne Holstege, Marc Hulsman, Camille Charbonnier et al. · Nature Genetics · 2022 · 219 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17