Duan Ni

Cross-talk of four types of RNA modification writers defines tumor microenvironment and pharmacogenomic landscape in colorectal cancer

Huifang Chen, Jiameng Yao, Rujuan Bao et al. · Molecular Cancer · 2021 · 262 citations · Full text

Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design

Shaoyong Lu, Xinheng He, Zhao Yang et al. · Nature Communications · 2021 · 214 citations · Full text

Allosteric Modulator Discovery: From Serendipity to Structure-Based Design

Shaoyong Lu, Xinheng He, Duan Ni et al. · Journal of Medicinal Chemistry · 2019 · 161 citations · Full text

Allosteric Modulators, Drug Target, Engineering +17

Discovery of cryptic allosteric sites using reversed allosteric communication by a combined computational and experimental strategy

Duan Ni, Jiacheng Wei, Xinheng He et al. · Chemical Science · 2020 · 128 citations · Full text

Deactivation Pathway of Ras GTPase Underlies Conformational Substates as Targets for Drug Design

Shaoyong Lu, Duan Ni, Chengxiang Wang et al. · ACS Catalysis · 2019 · 90 citations

Drug Target, Engineering, Deactivation Pathway +24