Andrew J. Ratcliffe

Generation of α-D-glucopyranosylacetonitrilium ions. Concerning the reverse anomeric effect

Andrew J. Ratcliffe, Bert Fraser‐Reid · Journal of the Chemical Society Perkin Transactions 1 · 1990 · 155 citations

Reverse Anomeric Effect, Bioorganic Chemistry, Engineering +14

Selective Type IV Phosphodiesterase Inhibitors as Antiasthmatic Agents. The Syntheses and Biological Activities of 3-(Cyclopentyloxy)-4-methoxybenzamides and Analogs

Michael J. Ashton, David Cook, Garry Fenton et al. · Journal of Medicinal Chemistry · 1994 · 112 citations · Full text

Antiparasitic Agent, Pde Iv, Biological Activities +17

The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy

Iain M. McLay, Frank Halley, John E. Souness et al. · Bioorganic & Medicinal Chemistry · 2001 · 78 citations

Rheumatoid Disorder, Rheumatology, Anti-inflammatory +8

n-Pentenyl glycosides as efficient synthons for promoter-mediated assembly of n-.alpha.-linked glycoproteins

Andrew J. Ratcliffe, Peter Konradsson, Bert Fraser‐Reid · Journal of the American Chemical Society · 1990 · 67 citations

Promoter-mediated Assembly, Bioorganic Chemistry, Engineering +19

Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors

Mahbub Alam, Rebekah E. Beevers, Tom Ceska et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 59 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +10