Concepedia

Tom Ceska

TC

Statistics

Publications

18

Citations

1.2K

H-Index

16

Active since

2007

Affiliations

UCB Pharma (United Kingdom)(Current)

UCB Pharma (Belgium)

UCB Pharma (United States)

King's College London

Paul Scherrer Institute

Tom Ceska is an author at UCB Pharma (United Kingdom) specializing in structural biology, ligand binding, and pharmacology.

Publications per year

2007–2022

18

Publications

18

Binding Mode and Structure–Activity Relationships around Direct Inhibitors of the Nrf2–Keap1 Complex

Eric Jnoff, Claudia Albrecht, John J. Barker et al. · ChemMedChem · 2014 · 174 citations

, , +16

Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer

James P. O’Connell, John Porter, Boris Kroeplien et al. · Nature Communications · 2019 · 131 citations · Full text

, , +12

Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A

Roger Benoit, Daniel Frey, Manuel Hilbert et al. · Nature · 2013 · 128 citations

, , +16

Crystal structure of the adenosine A <sub>2A</sub> receptor bound to an antagonist reveals a potential allosteric pocket

Bingfa Sun, Priti Bachhawat, Matthew Chu et al. · Proceedings of the National Academy of Sciences · 2017 · 128 citations · Full text

, , +17

Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF

David McMillan, C. Martinez-Fleites, John Porter et al. · Nature Communications · 2021 · 90 citations · Full text

, , +15

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