David McMillan

Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau

Jean‐Philippe Courade, Rachel Angers, Georges Mairet‐Coello et al. · Acta Neuropathologica · 2018 · 136 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer

James P. O’Connell, John Porter, Boris Kroeplien et al. · Nature Communications · 2019 · 131 citations · Full text

Medicine, Immunology, Pharmacology +12

Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A

Roger Benoit, Daniel Frey, Manuel Hilbert et al. · Nature · 2013 · 128 citations

Life Sciences, Neurobiology, Neuroscience +16

Distinctive binding properties of human monoclonal LGI1 autoantibodies determine pathogenic mechanisms

Melanie Ramberger, Antonio Berretta, Jeanne M.M. Tan et al. · Brain · 2020 · 128 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Characterization of the Interaction of Sclerostin with the Low Density Lipoprotein Receptor-related Protein (LRP) Family of Wnt Co-receptors

Gill Holdsworth, Patrick M. Slocombe, Carl Doyle et al. · Journal of Biological Chemistry · 2012 · 97 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13